Kesar /Saffron Saffron is a spice harvested by hand from the Crocus sativus flower, commonly known as the â??saffron crocus.â?? The term â??saffronâ?? points to the stigma of the flower. Saffron is the most expensive spice in the world with 1 pound costing between around 500 and 5,000 U.S. dollars. The Saffron exporter in India exports huge quantities of Saffron each year to many countries.