Pentaeptide-18 reduces the depth of facial wrinkles caused by facial expression muscle contraction,especially around the forehead and eyes.It uses a new way to target the wrinkle formation mechanism that expresses wrinkles in vitro,and provides an alternative method that can be combined with acetyl hexapeptide-3 and other peptides are used in combination.It can be incorporated into cosmetic formulations such as emulsions,gels and waxes.