Introduction: Spirulina is a biomass of cyanobacteria (blue-green algae) that can be consumed by humans and animals. Spirulina used as a dietary supplement or whole food. It is also used as a feed supplement in the aquaculture, aquarium, and poultry industries. Dried spirulina contains 5% water, 24% carbohydrates, 8% fat, and about 60% protein Spirulina, as nutrient-rich dietary supplement, supplies calories and is a rich source of numerous essential nutrients,particularly protein, B vitamins (thiamin, riboflavin, and niacin ), and dietary minerals, such as iron and manganese. Providing the fatty acids, gamma-linolenic acid, alpha-linolenic acid, linoleic acid, stearidonic acid, eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and arachidonic acid.