Product Name: CROSCARMELLOSE SODIUM Appearance: White Powder Soluble: Good solubility in water CAS No: 74811-65-7 EINECS No: 1312995-182-4 Supplier: ZHENYIBIO Croscarmellose sodium is used in oral pharmaceutical formulations as a disintegrant for capsules,tablets, and granules. In tablet formulations, croscarmellose sodium may be used in bothdirect-compressionandwet-granulationprocesses.Whenused in wet granulations, the croscarmellose sodium should be added in both the wet and dry stages of the process (intra- and extragranularly) so that the wicking and swelling ability of the disintegrant is best utilized. Croscarmellose sodium at concentrations up to 5% w/w may be used as a tablet disintegrant, although normally 2% w/w is used in tablets prepared by direct compression and 3% w/w in tablets prepared by a wet-granulation process.
