Molecular Formula: C17H21NO3.HBr;C17H22BrNO3
Molecular Weight: 368.27
CAS No: 1953-04-4
EINECS No.:217-780-5
Melting Point : 258~264
Solubility: Soluble in water,and slightly in alcohol.
Appearance: White to whitish crystal powder, oderless and tasteless.
Pharmacology Action:
Galanthamine extract is specific, competitive and reversible acetylcholinesterase inhibitor. It is also an allosteric modulator at nicotinic cholinergic receptor sites potentiating cholinergic nicotinic neurotransmission. Both the acetylcholine and nicotine receptors have been suggested as areas related to cognitive impairment. Initially, Galanthamine extract was used in anesthesiology to antagonize the effects of non-depolarizing muscle relaxants, and since then it was rapidly introduced in other areas of medicine, i.e. neurology, ophthalmology, gastroenterology, intensive care and resuscitation, cardiology, physiotherapy.
Galanthamine extract is a product with broad therapeutic index, allowing "soft" manifestation of its effect with individual dosing depending on the particular case.
Several trials already showed that Galantamine 16 and 24 mg/day significantly benefits the cognitive, functional, and behavioral symptoms of AD as compared with placebo and proved also to be very effective in symptomatic treatment of senile dementia of Alzheimer's type.
As clents requirement.
Product specificationú¦98% galanthamine hydrobromide Latin name: lycoris radiata (l.Herit.) Product type: white to off-white crystalline powder Part of the plant usedú¦tuber (fresh, 100% natural) Extract methodú¦hydro-alcoholic extraction Cas#ú¦[1953-04-4] Where will be galanthamine hydrobromide use to ? Anesthesiology Use for neurology Use for ophthalmology Use for gastroenterology, intensive care and resuscitation, cardiology, physiotherapy Packing detail Packed in paper-drums and two plastic-bags inside. Net weight: 1kg/aluminum bag. Storage situation Stored in a cool and dry well-closed container, keep away from moisture and strong light / heat. Shelf life Two years under well storage situation and stored away from direct sun light.
Pharmacology action: Galanthamine extract is specific, competitive and reversible acetylcholinesterase inhibitor. It is also an allosteric modulator at nicotinic cholinergic receptor sites potentiating cholinergic nicotinic neurotransmission. Both the acetylcholine and nicotine receptors have been suggested as areas related to cognitive impairment. Initially, galanthamine extract was used in anesthesiology to antagonize the effects of non-depolarizing muscle relaxants, and since then it was rapidly introduced in other areas of medicine, i.E. Neurology, ophthalmology, gastroenterology, intensive care and resuscitation, cardiology, physiotherapy. Galanthamine extract is a product with broad therapeutic index, allowing "soft" manifestation of its effect with individual dosing depending on the particular case. Several trials already showed that galantamine 16 and 24 mg/day significantly benefits the cognitive, functional, and behavioral symptoms of ad as compared with placebo and proved also to be very effective in symptomatic treatment of senile dementia of alzheimer's type.
