Triluma cream is a prescription skincare treatment used to address moderate to severe melasma, a skin condition characterized by dark patches. It contains three active ingredients: fluocinolone acetonide (a corticosteroid), hydroquinone (a skin-lightening agent), and tretinoin (a retinoid). This combination works by reducing the production of melanin in the skin, lightening existing dark spots, and preventing the formation of new ones. Triluma is typically applied once daily in the evening, following a thorough cleansing of the skin. It's important to use sunscreen during the day and follow your dermatologist's instructions carefully to achieve the best results and minimize the risk of side effects.