Ethylhexyl Salicylate

2-Ethylhexyl Salicylate, or octyl salicylate, is an organic compound used as an ingredient in sunscreens and cosmetics to absorb UVB (ultraviolet) rays from the sun. It is an ester formed by the condensation of salicylic acid with 2-ethylhexanol. It is a colorless oily liquid with a slight floral odor.
The salicylate portion of the molecule absorbs ultraviolet light, protecting skin from the harmful effects of exposure to sunlight. The ethylhexanol portion is a fatty alcohol, adding emollient and oil-like (water resistant) properties.
Test Items Specifications Results
Appearance Colorless to pale yellow liquid Colorless liquid
Odour Slight characteristic Slight characteristic
Identity (IR) USP<197F> Matches reference spectrum Matches reference spectrum
Identity (Retention time) USP<621> Matches reference retention time Matches reference retention time
UV Specific extinction
(E1%1cm,310nm, ethanol) USP<197U> 165-185 175
Specific gravity(25ºC) USP<841> 1.011-1.016 1.015
Refractive index(20ºC) USP<831> 1.500-1.503 1.503
Acidity(ml/ml) Titration (USP) 0.2 0.0ml/ml
Chromatographic purity GC USP<621> Purity (%) 99.0 99.6
Ethylhexanol(%) 0.1 <0.6ppm (LOD)
Methyl salicylate (%) 0.1 <2.3ppm (LOD)
Each impurity (%) 0.5 0.2
Total impurities (%) 2.0 0.4
Assay (%) USP<621> 95.0-105 100.9
Conclusion Meet all the requirements of USP standards

2-Ethylhexyl Salicylate, or octyl salicylate, is an organic compound used as an ingredient in sunscreens and cosmetics to absorb UVB (ultraviolet) rays from the sun. It is an ester formed by the condensation of salicylic acid with 2-ethylhexanol. It is a colorless oily liquid with a slight floral odor.
The salicylate portion of the molecule absorbs ultraviolet light, protecting skin from the harmful effects of exposure to sunlight. The ethylhexanol portion is a fatty alcohol, adding emollient and oil-like (water resistant) properties.
Test Items Specifications Results
Appearance Colorless to pale yellow liquid Colorless liquid
Odour Slight characteristic Slight characteristic
Identity (IR) USP<197F> Matches reference spectrum Matches reference spectrum
Identity (Retention time) USP<621> Matches reference retention time Matches reference retention time
UV Specific extinction
(E1%1cm,310nm, ethanol) USP<197U> 165-185 175
Specific gravity(25�?�ºC) USP<841> 1.011-1.016 1.015
Refractive index(20�?�ºC) USP<831> 1.500-1.503 1.503
Acidity(ml/ml) Titration (USP) 0.2 0.0ml/ml
Chromatographic purity GC USP<621> Purity (%) 99.0 99.6
Ethylhexanol(%) 0.1 <0.6ppm (LOD)
Methyl salicylate (%) 0.1 <2.3ppm (LOD)
Each impurity (%) 0.5 0.2
Total impurities (%) 2.0 0.4
Assay (%) USP<621> 95.0-105 100.9
Conclusion Meet all the requirements of USP standards

2-Ethylhexyl Salicylate, or octyl salicylate, is an organic compound used as an ingredient in sunscreens and cosmetics to absorb UVB (ultraviolet) rays from the sun. It is an ester formed by the condensation of salicylic acid with 2-ethylhexanol. It is a colorless oily liquid with a slight floral odor.
The salicylate portion of the molecule absorbs ultraviolet light, protecting skin from the harmful effects of exposure to sunlight. The ethylhexanol portion is a fatty alcohol, adding emollient and oil-like (water resistant) properties.
Test Items Specifications Results
Appearance Colorless to pale yellow liquid Colorless liquid
Odour Slight characteristic Slight characteristic
Identity (IR) USP<197F> Matches reference spectrum Matches reference spectrum
Identity (Retention time) USP<621> Matches reference retention time Matches reference retention time
UV Specific extinction
(E1%1cm,310nm, ethanol) USP<197U> 165-185 175
Specific gravity(25ºC) USP<841> 1.011-1.016 1.015
Refractive index(20ºC) USP<831> 1.500-1.503 1.503
Acidity(ml/ml) Titration (USP) 0.2 0.0ml/ml
Chromatographic purity GC USP<621> Purity (%) 99.0 99.6
Ethylhexanol(%) 0.1 <0.6ppm (LOD)
Methyl salicylate (%) 0.1 <2.3ppm (LOD)
Each impurity (%) 0.5 0.2
Total impurities (%) 2.0 0.4
Assay (%) USP<621> 95.0-105 100.9
Conclusion Meet all the requirements of USP standards