Helichrysum essential oil comes from a natural medicinal plant thatâ??s used to make a beneficial essential oil that boasts many different full-body benefits due to its anti-inflammatory, antioxidant, antimicrobial, antifungal and antibacterial properties. (1) Helichrysum essential oil, typically from the Helichrysum italicum plant, has been established in various experimental studies to have strong abilities to lower inflammation due to several mechanisms: inflammatory enzyme inhibition, free radical scavenging activity and corticoid-like effects.