Safflower seed oil is used for preventing heart disease, including hardening of the arteries (atherosclerosis) and stroke. It is also used to treat fever, tumors, coughs, breathing problems, clotting conditions, pain, heart disease, chest pain, and traumatic injuries. Some people use it for inducing sweating; and as a laxative, stimulant, antiperspirant, and expectorant to help loosen phlegm