Reyoungel Fine --- With the smallest particles for the correction of very thin, superficial lines. Injected in the upper part of the dermis. Reyoungel Derm --- Medium particle size for moderate wrinkles. Injected in the middle part of the dermis. Reyoungel Deep --- Larger particles for deep folds. Injected in the deep layer of the dermis and/or the surface layer of the subcutis. Needle size 27G.