Piperine is a naturally occurring alkaloid found in the fruits of the black pepper plant (Piper nigrum). It is responsible for the pungency of black pepper, and it is commonly used as a food additive, as a natural flavoring and coloring agent. Piperine is also used as a dietary supplement, it is known to enhance the bioavailability of other supplements and nutrients, such as curcuminoids found in turmeric, beta-carotene, and selenium. Piperine oil is extracted from black pepper and it is a concentrated form of the alkaloid. It is commonly used as a food additive, as a natural flavoring and coloring agent, as well as in supplements. It is also being researched for its potential therapeutic benefits, it is said to have antioxidant, anti-inflammatory, anti-cancer and anti-obesity properties. However, more research is needed to confirm these effects. It should be used with caution and be avoided during pregnancy or with certain medications, always consult with a healthcare professional before use.