What is nitrile? Nitrile is a material whose molecule is obtained by substituting an organic radical for a hydrogen atom in hydrocyanic acid. It is a synthetic rubber similar to latex but does not contain its allergens as it is made of synthetic latex. The nitrile gloves offer three times greater resistance to microholes than conventional latex gloves, in addition to offering more comfort and elasticity. Sizes: XS, S, M, L and XL.