Cooling agent is the general term for all chemical substances that produce a cooling effect with wild medicine. Among all WS-23 is a new-structured amide cooling agent, which can produce strong impact coolness and continue to act on the tongue and upper jaw. It is a kind of cooling agent widely used in food, medicine and other fields, like gum, toothpaste and candy. WS-23 is white crystalline and almost odorless while it is characterized by strong mint-like cool taste.