COZING-WS11C indications: A, product efficacy 1. To purify the blood 2. The flow of blood 3. stroke and brain injury Second, the product scope 1. Patients with cerebrovascular disease 2. The three tenors crowd 3. The healthy people 4. People with poor sleep 5. Rhinitis crowd LLLT for Stroke and Brain Injury In the first clinical trial, PBM(Pharmacy benefit management) was applied within 24 hours of a stroke and the study noted statistically significant improvements when administered at 18 hours post-stroke, over the entire surface of the head regardless of the type of stroke. Only one laser treatment was administered, and results were present 5 days later. At 90 days post-stroke, 70 percent of the patients treated with LLLT still showed a significantly successful outcome. What is Low-level laser therapy (LLLT)? Low-level laser therapy (LLLT), also known as photobiomodulation, is an emerging therapeutic approach in which cells or tissues are exposed to low-levels of red and near-IR light. Its experimental applications have broadened to include serious diseases such as heart attack,stroke, and spinal cord injury. LLLT may have beneficial effects in the acute treatment of TBI by increasing mitochondrial respiration, activating transcription factors, reducing key inflammatory mediators, inhibiting apoptosis (programmed cell death), stimulating angiogenesis, and increasing neurogenesis A second clinical trial determined LLLT treatment to be effective for moderate to severe strokes, but not severe. The third clinical trial was inconclusive for any significant results. There is some evidence to suggest that the time between the occurrence of a stroke and initiation of the PBM treatment may be an important factor. PBM is proving helpful in brain injury recovery in numerous studies. In experiments with mice. those treated with LLLT had significantly reduced neurological deficits, including smaller loss of cortical tissue, better mobility, less depression and anxiety, increased BDNF, and better learning and memory. In one small study with humans having TBIs ranging from 10 months to 8 years old, application of red and near infrared light emitting diodes (LED) three times a week for 10 minutes over six weeks significantly improved executive function, verbal learning, free recall, sleep, and decreased PTSD symptoms.