In pyrogen testing on rabbits, a telethermometer plays a crucial role in monitoring body temperature changes. Here's how it's used: Temperature Measurement: Pyrogen testing involves the administration of a test substance (e.g., potential pharmaceutical products or medical devices) to the rabbit, followed by monitoring for signs of fever (pyrexia). A telethermometer is used to continuously measure the rabbit's body temperature before and after the administration of the test substance. Baseline Measurement: Before conducting the test, baseline body temperature readings are taken to establish a reference point. This helps in identifying any deviations from the normal temperature range during the test period. Detection of Pyrogenic Response: Following the administration of the test substance, the rabbit's body temperature is monitored closely using the telethermometer. An increase in body temperature above a predefined threshold indicates a pyrogenic response, suggesting the presence of fever-inducing substances (pyrogens) in the test substance. Real-time Monitoring: A telethermometer allows for real-time monitoring of body temperature changes, providing researchers with immediate feedback on the rabbit's physiological response to the test substance. This enables prompt decision-making regarding the continuation or termination of the test based on the observed pyrogenic response. Data Recording and Analysis: Telethermometers often come with data recording capabilities, allowing researchers to log temperature measurements at regular intervals throughout the testing period. This data can be analyzed to assess the onset, duration, and magnitude of the pyrogenic response, aiding in the interpretation of test results. Animal Welfare: Continuous temperature monitoring with a telethermometer helps ensure the welfare of the test animals by enabling early detection of fever and prompt intervention if necessary. This minimizes potential discomfort or distress experienced by the animals during the testing process. Overall, the use of a telethermometer in pyrogen testing on rabbits enhances the accuracy, reliability, and efficiency of the testing procedure, ultimately contributing to the safety evaluation of pharmaceutical products and medical devices intended for human use.
Grip strength meters are commonly used in research settings to assess the muscular strength of rodents, including rats and mice. Here's how they are utilized: Muscular Function Assessment: Grip strength meters provide a quantitative measure of the muscular strength of rodents by assessing their ability to grasp and hold onto a horizontal bar or grid with their forelimbs. This measurement reflects the overall neuromuscular function and is particularly useful in studies focused on muscle physiology, aging, neuromuscular disorders, and drug efficacy testing. Phenotypic Characterization: Grip strength measurements can be used as part of phenotypic characterization in animal models. Differences in grip strength between groups of rodents, such as strains, genders, ages, or experimental conditions, can provide insights into genetic factors, aging processes, disease progression, or the effects of interventions. Neurological and Neuromuscular Disorders: Grip strength meters are valuable tools for studying neurological and neuromuscular disorders in rodents. Changes in grip strength can indicate motor deficits associated with conditions such as muscular dystrophy, amyotrophic lateral sclerosis (ALS), spinal cord injury, or peripheral neuropathy. Researchers can use grip strength measurements to track disease progression, evaluate therapeutic interventions, or screen potential drug candidates. Pharmacological Studies: Grip strength assessments are often included in pharmacological studies to evaluate the effects of drugs or treatments on muscular function. For example, researchers can investigate the impact of muscle relaxants, analgesics, or muscle-building agents on grip strength in rodent models. These studies help assess the safety and efficacy of therapeutic interventions targeting muscular function. Aging Research: Grip strength measurements are commonly used in aging research to assess age-related changes in muscular function and frailty in rodents. By longitudinally monitoring grip strength in aging animals, researchers can evaluate the progression of age-related decline in muscular strength and explore interventions to mitigate age-associated deficits. Overall, grip strength meters serve as valuable tools for assessing muscular function and studying a wide range of physiological and pathological conditions in rodent models, contributing to our understanding of neuromuscular biology and the development of therapeutic strategies.
Digital plethysmometers can indeed be used to measure edema in rodent models. Here's how they can be applied for this purpose: Paw Volume Measurement: One common method involves measuring changes in paw volume as an indicator of edema formation. The rodent's paw is placed in a chamber connected to the digital plethysmometer. By measuring the displacement of water or air caused by the paw, the instrument can accurately quantify changes in paw volume over time. Inflammatory Models: In research settings, edema is often induced by inflammatory stimuli such as carrageenan injection or trauma. Digital plethysmometers allow researchers to monitor the progression of edema by measuring changes in paw volume at various time points post-induction. Drug Screening: Researchers can use digital plethysmometers to evaluate the efficacy of anti-inflammatory drugs or compounds in reducing edema formation. By comparing paw volume measurements between treated and untreated groups, the effectiveness of potential therapeutics can be assessed. Genetic Studies: Digital plethysmometers are also useful in studying the genetic basis of edema formation. By comparing edema responses between different strains of rodents or genetically modified models, researchers can identify genes or pathways involved in regulating inflammation and fluid accumulation. Longitudinal Monitoring: Digital plethysmometers enable longitudinal monitoring of edema progression and resolution over time. This longitudinal approach provides valuable insights into the dynamics of edema formation and the temporal effects of interventions.
1. One machine is multi-purpose, especially suitable crushing and recycling of building concrete and mou road construction, with good flexibility and cost adv 2. Adopt advanced hydraulic technology, use hydrau motor to drive the jaw plate to rotate, crush concret stones, etc., to meet the set requirements. 3.Crushing jaw plates can be easily replaced on-site. The jaws are identical and can be ro tated 180 degrees to even out wear. 4.Efficient Work Optimal design of jaw plates bring higher efficient of crushing. Saving fuel consumption by minimized operating system.
Disc granulator (also known as the ball plate) adopts the whole circular arc structure, and the granulating rate can reach more than 93%. It has three discharging ports, which is convenient for discontinuous production, greatly reducing the labor intensity and improving the labor efficiency. The reducer and motor use flexible belt drive to start smoothly, slow down the impact force and improve the service life of the equipment. The plate bottom is strengthened by a plurality of radiant steel plates, which is durable and never deformed. It is an ideal equipment for organic fertilizer and compound fertilizer, which is designed with thick, heavy and strong base, so it has no fixed anchor bolts and smooth operation.
Freeze with CPF (Contact Plate Freezer) ensuring to lock the freshness and quality. Frozen Condition, Size(cm): 10-15, 16-20, 21-25, 26-30, 30-up. Packed in Box (9.2kg/Box)
Freeze with CPF (Contact Plate Freezer) ensuring to lock the freshness and quality. Grade A, B, AA, BAA Size: 100-200, 200-300, 300-500, 500-700, 700-1000. Packed in Box (9.2Kg/Box)
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DIN 1.2344 tool steel round bar, flat bar, and plate. 1.2344 Tool Steel/H13 steel is chromium hot work tool steels which are widely used in hot and cold work tooling applications.
DIN 1.2344 tool steel round bar, flat bar, and plate. 1.2344 Tool Steel/H13 steel is chromium hot work tool steels which are widely used in hot and cold work tooling applications.
2000 Komori L-428 EH, KMS IV (Komori Monitoring System) Impressions:107 mio. Color(s): 4Size: 520 x 720 mm Komori PCC for CIP 3 connection KPS-2 PQC Register remote control AMR automatic make ready system Chromed impression cylinders Chromed plate cylinders Komorimatic Conventional sidelay Steel plate in feeder Stream feeder Electromecanic double sheet control Beil Registersystem SAPC semi-automatic plate change Steel plate in delivery Grafix Digitronic powder spray Powder spray All washing devices Techno Trans Aplha C PPC 4 with calebrating files from CIP3 Speed: 15000/
Product Introduction: Carton Brush for rotogravure Electroplating machine used for gravure cylinder Electroplating tank. Application for nickel/copper/chrome plating machine, dechroming, degreasing machine etc Product Advantage: Good electrical conductivity
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Product Introduction: Titanium Basket for gravure plating machine used on rotogravure cylinder making copper and chrome tank. Product Advantage: 1.Good corrosion resistance against 2.Good electrical conductivity
Dinner set crockery, often referred to as dinnerware, is a collection of dishes, plates, bowls, and other tableware items used for serving and eating food. These sets are designed not only for practicality but also to enhance the aesthetics of your dining table .
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