What is nucleic acid detection, that is, after collecting human secretions, under laboratory conditions, by analyzing the RNA gene sequence of the virus, using PCR amplification method for detection, and diagnosis of clinical etiology. At present, nucleic acid testing is the most effective testing method for early determination of whether a patient is infected with the virus, early detection and early treatment.
Nucleic acid detection swabs are divided into two types: nasal swabs and throat swabs. During the sampling process, the doctor will use a swab like a cotton swab to wipe the pharynx and tonsils, or the secretions around the nasal cavity. One touch", quick and painless. Medical institutions will disinfect the inspection area, and medical staff will also disinfect their hands to avoid cross-infection. Generally speaking, the sampling process is safe and clean, without worrying about the risk of infection.
So which types of swab preservation solutions are divided into after sampling? There are two types of swab preservation solutions, inactivated and non-inactivated. At the beginning, almost all types of swab preservation solutions used in the market directly preserve live viruses. Inactivated swab preservation solution. This preservation method will cause the medical staff in sampling, transportation and testing to face a higher risk of infection. In response to this situation, the front line of anti-epidemics needs to store swabs that can directly inactivate the virus. However, it should be noted that while inactivating the virus, it should also be considered whether the preservation solution can stably preserve the integrity of the viral nucleic acid, so as to prevent the nucleic acid in the sample from degrading before the test, resulting in "false negative" nucleic acid testing. The production of the inactivated virus preservation solution developed to avoid this problem.
To put it simply, nucleic acid detection swab preservation solutions can be divided into two categories. The inactivated preservation solution developed by Desheng is a swab preservation solution with lysis function, which contains lysis salts for inactivating viruses and lysis proteins to protect nucleic acids. The virus preservation and lysis are completed in one step. The other is a non-inactivated type of preservation solution. Contrary to the inactivated type, it can protect the integrity of the virus protein and nucleic acid. In addition to nucleic acid detection, it can also be used for virus culture research. The operating environment requirements for this preservation solution are also different. The inactivated environment does not need to be so strict, while the non-inactivated type has higher operating environment requirements due to the risk of virus infection.
