Hereme hyaluronic acid fillers biodegradable gel made of non-animal cross-linked hyaluronic acid. Â deep type hyaluronic acid filler are used for deep wrinkle removal, such as chin and nose contour, face contour, nasolabial, glabellar wrinkles. And its effect can keep 6-12 months Indication: Deep wrinkle removal, chin and nose contour, face contour, nasolabial, forehead wrinkle.