Zingiber officinale, commonly known as ginger, is a spice consumed worldwide for culinary and medicinal purposes. The plant has a number of chemicals responsible for its medicinal properties, such as antiarthritis, antiinflammatory, antidiabetic, antibacterial, antifungal, anticancer, etc. The present chapter compiled scientific data retrieved from websites, such as PubMed, ScienceDirect, Scopus, Web-of-Knowledge, Google Scholar, and others related to the phytochemistry and pharmacology of ginger. A synopsis of the world production of the plant as well as some patents related to Z.