2-methyl-tetrahydrofuran is the main raw material for the synthesis of chloroquine phosphate and primaquine phosphate. As a green solvent, 2-methyl tetrahydrofuran can replace tetrahydrofuran as grigner reaction solvent, and can also replace benzene, Solvents such as toluene and chloroform are widely used in the synthesis of pharmaceutical intermediates, fragrances and new materials.